Over time, SLE can damage or cause complications in systems throughout your body. Possible complications may include:. SLE can have serious negative effects on your body during pregnancy. It can lead to pregnancy complications and even miscarriage. Talk with your doctor about ways to reduce the risk of complications. SLE affects people differently. Treatments are most effective when you start them soon after symptoms develop and when your doctor tailors them to you.
Living with a chronic condition can be difficult. Talk to your doctor about support groups in your area. Working with a trained counselor or support group can help you reduce stress , maintain positive mental health, and manage your illness. Historically, lupus caused people to die young. Today, with careful treatment, most people with lupus can expect to live a normal lifespan. Learn more. There is no established diet for lupus. However, eating some foods and avoiding others may help you manage your symptoms.
Autoimmune disease occurs when your immune system…. Lupus is an unpredictable disease of flares and remissions, so finding the most effective treatment can be tricky. Learn how to effectively assess…. Health Conditions Discover Plan Connect.
Medically reviewed by Brenda B. SLE is more common in women than men by nearly 10 to 1. It may occur at any age. However, it appears most often in young women between the ages of 15 and Symptoms vary from person to person, and may come and go. Everyone with SLE has joint pain and swelling at some time. Some develop arthritis. SLE often affects the joints of the fingers, hands, wrists, and knees. To be diagnosed with lupus, you must have 4 out of 11 common signs of the disease.
Nearly all people with lupus have a positive test for antinuclear antibody ANA. However, having a positive ANA alone does not mean you have lupus. The health care provider will do a complete physical exam. You may have a rash, arthritis, or edema in the ankles. There may be an abnormal sound called a heart friction rub or pleural friction rub. Your provider will also do a nervous system exam.
There is no cure for SLE. The goal of treatment is to control symptoms. Severe symptoms that involve the heart, lungs, kidneys, and other organs often need treatment by specialists. Each person with SLE needs evaluation regarding:. Counseling and support groups may help with the emotional issues involved with the disease.
The outcome for people with SLE has improved in recent years. Many people with SLE have mild symptoms. How well you do depends on how severe the disease is. Most people with SLE will require medicines for a long time. Nearly all will require hydroxychloroquine indefinitely. However, in the United States, SLE is one of the top 20 leading causes of death in females between the ages of 5 and Many new medicines are being studied to improve the outcome of women with SLE. Many women with SLE can get pregnant and deliver a healthy baby.
A good outcome is more likely for women who receive proper treatment and do not have serious heart or kidney problems. However, the presence of certain SLE antibodies or antiphospholipid antibodies raises the risk of miscarriage.
Some people with SLE have abnormal immune deposits in the kidney cells. This leads to a condition called lupus nephritis. People with this problem may develop kidney failure. They may need dialysis or a kidney transplant. Recent national estimates of prevalence and incidence are not available for SLE. SLE is relatively uncommon, is difficult to diagnose, and is not a reportable disease, so it is expensive to capture all diagnosed cases reliably for epidemiologic studies.
There are no recent studies to determine if SLE prevalence or incidence are changing over time. See the Lupus Studies page for more information. Prevalence is a measurement of all individuals affected by a disease at a particular time, usually a year.
Older national prevalence estimates vary widely due to differences in case definitions, small study populations, and study methods.
Results from the CDC Lupus registries estimated that annual prevalence from — was much higher for blacks than whites in Michigan Washtenaw and Wayne Counties Annual prevalence estimates were much higher among women than men in Michigan 9.
Incidence is a measurement of the number of new cases of individuals who contract a disease during a particular period of time, often a year. Recent national incidence estimates are not available for SLE. National incidence data are difficult to obtain because it is relatively expensive to capture all diagnosed cases reliably learn more about SLE prevalence and incidence above and the year of onset is hard to determine slowly developing, non-specific symptoms and signs , so resource-intense studies must be done in small areas.
Annual incidence estimates were much higher for women than men in Michigan 9. Causes of premature death associated with SLE are mainly active disease, organ failure e. Using death certificates for US residents, SLE was identified as the underlying cause of death for an average of 1, deaths per year from — CDC has previously funded five lupus registries and the development of a public health agenda Cdc-pdf External to guide public health efforts.
Currently, CDC is funding work on several SLE-relevant activities, such as three follow-up studies and research for self-management.
For more information, visit the CDC-funded activities page. SLE is the most common and most serious type of lupus. Other types of lupus include the following:. Cutaneous lupus skin lupus is lupus that affects the skin in the form of a rash or lesions. This type of lupus can occur on any part of the body, but usually appears where the skin is exposed to sunlight. Drug-induced lupus is similar to SLE, but occurs as the result of an overreaction to certain medications.
Symptoms usually occur 3 to 6 months after starting a medication, and disappear once the medicine is stopped.
Neonatal lupus occurs when an infant passively acquires auto-antibodies from a mother with SLE. Top of Page. Section Navigation.
0コメント